C3.ai Secures Partnership with U.S. Department of Health and Human Services
In a groundbreaking announcement on December 4, 2025, C3.ai, Inc. revealed that its Agentic AI platform has been selected by the U.S. Department of Health and Human Services (HHS) to serve as a data foundation across the National Institutes of Health (NIH) and the Centers for Medicare & Medicaid Services (CMS).
This selection underscores C3.ai’s pivotal role in shaping health informatics and enhancing data accessibility for these vital institutions.
Stock Market Reactions
- Current Stock Price: $15.00 USD
- 5-Day Change: -0.07%
- Year-to-Date Change: +4.08%
- First Quarter Change: -56.32%
On the same day, C3.ai shared its fiscal second-quarter earnings report, which indicated a decline in revenue, further contributing to overall fluctuations in stock performance. Market analysts expressed concerns about the company’s trajectory, suggesting a need for strategic recalibrations.
Quarterly Earnings and Market Sentiment
C3.ai’s recent earnings call presented sobering figures: the company reported an adjusted loss, evolving from a revenue of $75.1 million, slightly surpassing FactSet estimates of $74.9 million. This reflects a growing divergence between analyst expectations and actual performance metrics.
Projected Financial Outlook

Looking ahead, C3.ai has indicated an anticipated revenue range of $72 million to $80 million for the forthcoming quarter, instilling cautious optimism despite the tumultuous backdrop.
Analysts maintain a consensus rating of underperform, with an average price target set at $14.67 USD, suggesting a 2.29% downward potential based on current market standings.
As the company navigates its future, the emphasis will be on reinforcing strategic initiatives and leveraging technology to enhance operational efficiencies, especially within the burgeoning field of healthcare AI.
Source link: Marketscreener.com.






