News Summary:
- This declaration denotes a pivotal advancement in the secure AI infrastructure landscape across the UAE, consistent with the US-UAE AI Acceleration Partnership.
- Cisco will empower, connect, and fortify a substantial AI cluster deployed by G42, showcasing AMD’s sophisticated MI350X GPUs.
- The partnership further solidifies the integration of esteemed US technology partners into G42’s AI infrastructure strategy.
SAN JOSE, Calif., and ABU DHABI, UAE, Oct. 28, 2025 /PRNewswire/ — Cisco (NASDAQ: CSCO), the preeminent leader in networking and security, has unveiled a significant expansion of its partnership with G42, the UAE’s foremost artificial intelligence authority, aimed at enhancing secure AI frameworks.
This initiative underscores Cisco’s enduring commitment to fostering digital progress in the region by constructing secure, reliable, and high-performance infrastructures suitable for the AI era.
A Trustworthy Infrastructure for the UAE’s AI Economy
Chuck Robbins, Chair & CEO of Cisco, and Peng Xiao, Group CEO of G42 in Abu Dhabi, today, Cisco will activate, interconnect, and safeguard a sprawling AI cluster introduced by G42, which is integrated with AMD’s advanced MI350X GPUs.
This deployment amalgamates Cisco’s comprehensive, secure AI infrastructure, encompassing compute, networking, security, storage, optics, alongside observability and analytics tools, thereby delivering scalable performance and unified management catered to the region’s most advanced AI workloads.
In addition, Cisco will assume the role of technology integrator within G42’s Regulated Technology Environment (RTE), a benchmark compliance and security framework designed to ensure the highest levels of protection, transparency, and governance for advanced computing infrastructures, effectively preventing any unauthorized access or misuse.
This partnership builds upon collaborative efforts under the broader US–UAE AI Acceleration Partnership, a pivotal program aimed at propelling bilateral technological aspirations, which includes flagship projects like the 1GW Stargate UAE cluster currently under development in Abu Dhabi, and the 5GW UAE-US AI technology campus announced during President Trump’s visit to the UAE in May 2025.
Peng Xiao, Group CEO of G42, remarked:
“This collaboration with Cisco signifies the next phase in fortifying trust and technological alignment between the US and UAE under the AI Acceleration Partnership.
It amplifies our mutual dedication to constructing high-performance, secure, sovereign, and compliant AI infrastructures that foster global innovation while adhering to stringent governance standards.”
Chuck Robbins, Chair and CEO of Cisco, expressed:
“Cisco is honored to deepen our alliance with G42, facilitating the UAE’s forthcoming wave of AI innovation by enforcing secure and trusted high-performance infrastructures.
This collaboration bolsters the US-UAE AI Acceleration Partnership and accentuates Cisco’s pivotal role in the UAE’s digital transformation journey. Together, we are shaping an infrastructure that embraces responsible innovation.”
Dr. Lisa Su, Chair and CEO, AMD, stated:
“AMD is delighted to collaborate with Cisco and G42 to power the next generation of AI infrastructure in the UAE. Our AMD Instinct MI350X accelerators furnish the performance, efficiency, and scalability essential for promoting secure and sovereign AI innovation.
This endeavor fortifies the UAE’s stature as a global leader in innovative AI development and exemplifies how initiatives like the US-UAE AI Acceleration Partnership can propel national digital ambitions.”
Propelling the Region’s Digital Momentum
According to Cisco’s recent AI survey, 92% of organizations within the UAE are planning to deploy AI agents, with 41% indicating they expect these agents to collaborate with employees within a year. However, merely 25% possess robust GPU capabilities.
This partnership seeks to bridge that gap by delivering scalable and secure AI infrastructures designed for expansion.
With AI rapidly emerging as the principal catalyst for innovation, Cisco’s involvement in the UAE’s digital transformation journey has never been more critical.
This collaboration embodies another decisive advancement in Cisco’s strategy – converting innovation into tangible impact and accelerating the region’s digital evolution.
Cisco’s Secure, Comprehensive AI Infrastructure
Cisco provides a distinctive end-to-end AI-ready data center solution that integrates compute, networking, security, automation, and optics.
The deployment will harness Cisco’s extensive AI-ready data center portfolio, employing Cisco UCS 885A servers with AMD MI350X GPUs for computing, high-speed Nexus 9K 800G switches for networking, as well as the VAST AI Operating System hosted on UCS servers, alongside Firepower 4200 next-generation firewalls for security, Nexus Dashboard, and Intersight for network automation and computing management.
Furthermore, it will incorporate the latest Cisco optics to assure supreme performance and reliability, complemented by Cisco Advanced Services for meticulous planning, design, and implementation.
This alliance further augments G42’s network of reputable US technology partners contributing to the Regulated Technology Environment (RTE) framework, reinforcing a model anchored in transparency and accountability.
G42 and Cisco will collaborate closely with relevant U.S. government agencies to secure necessary licenses and regulatory permissions for deployment, which is anticipated to advance in the coming months, pending final approvals.
About Cisco

Cisco (NASDAQ: CSCO) is the global technology frontrunner reshaping how organizations connect and protect in the AI epoch. For over four decades, Cisco has established secure connections across the globe.
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About G42
G42 is a technology holding group and a global pioneer in visionary artificial intelligence aimed at creating a better future. Founded in Abu Dhabi and operating on a global scale, G42 advocates AI as a potent force for good across various sectors.
From molecular biology to space exploration and every domain in between, G42 embodies exponential prospects today. For additional information, visit www.g42.ai
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