Trump Initiates ‘Genesis Mission’: A Landmark AI Initiative
On Monday, President Trump enacted an executive order launching the “Genesis Mission,” an ambitious national initiative aimed at harnessing artificial intelligence for scientific advancement. Officials hailed this endeavor as the most extensive federal research undertaking since the Manhattan Project.
The order mandates federal agencies to synergize disparate datasets, supercomputing capabilities from national laboratories, and newly developed AI technologies.
This integration is expected to expedite scientific breakthroughs across various disciplines while bolstering American technological supremacy.
Central to this initiative is the establishment of the American Science and Security Platform. According to the Department of Energy (DOE), this platform will seamlessly connect supercomputers, secure cloud-based AI environments, scientific datasets, simulation tools, and automated laboratory systems. This comprehensive framework is designed to enhance model training and facilitate AI-centric experimentation.
The executive order articulates, “The Genesis Mission will amalgamate our nation’s research and development resources. We will blend the expertise of distinguished American scientists—those at our national laboratories—with innovative American enterprises, esteemed academic institutions, and existing research infrastructure. This collaboration aims to dramatically expedite AI advancements and its applications.”
Officials from the White House Office of Science and Technology Policy and the DOE indicated that the Genesis Mission aspires to truncate research durations from years to mere days or even hours.
This transformation is purportedly achievable by integrating federal data with neural network models capable of making predictions, directing experiments, and executing simulations.
The initiative is committed to safeguarding copyright protections and national security protocols. Open data will be accessible to researchers, while proprietary or classified information will be restricted to sanctioned personnel.
According to a White House representative, we operate 28 user facilities and support 40,000 scientists and engineers.
While some datasets are proprietary, we also possess highly confidential materials not available to third parties. All three categories of data will be utilized, fostering ongoing partnerships based on their respective needs.
The order further stipulates that the DOE must implement federal classification, export-control, and cybersecurity standards for the new platform, in addition to vetting external researchers or organizations desiring access.
In response to queries about mitigating inaccuracies in the predictive models employed in the Genesis Mission, a White House official assured that every prediction would undergo rigorous validation against empirical results.
“These models are intended to produce forecasts and form strategies,” the official elaborated to Decrypt. “If the predictions deviate from data provided by scientific instruments, they are deemed erroneous. Through this iterative validation process, we will ensure the necessary accuracy to propel the Genesis Mission forward.”
Although the term AI was frequently invoked during the announcement, the official clarified that the administration does not refer to consumer-oriented chatbots like ChatGPT or Grok.
“Our discourse on AI pertains to capturing the fundamental knowledge inherent in physics, chemistry, and engineering within expansive neural networks,” the official stated.
“These neural networks extend beyond conventional large language models. Our approach will integrate core scientific principles with advanced model architectures.”
A Review of Trump’s Actions Regarding AI
The Genesis Mission follows a series of significant AI-related actions taken earlier in 2025. In January, the White House revoked an order from the Biden administration that mandated companies to submit evaluations of model safety testing.
The Trump administration contended that this policy hampered innovation. Later, in July, the government sought to eliminate “woke AI” by instructing federal agencies to endorse the development of AI systems devoid of ideological bias.
The administration has also reorganized federal oversight mechanisms, realigning them towards evaluation and competitiveness rather than the broader safety-testing framework of its predecessor.
Most recently, the administration is contemplating an executive order to institute a federal AI regulatory framework to combat state-level AI regulations.
The latest executive order instructs national laboratories to augment their existing supercomputing capabilities, linking them directly to scientific instrumentation.
This integration will empower AI systems to generate and verify predictions in real time. Officials noted that the United States already possesses several of the world’s leading supercomputers.
The order allocates the DOE 90 days to identify federal and cloud-based computing resources, 120 days for selecting initial datasets and models, and 240 days for reviewing robotic and automated laboratory systems. The department is also charged with demonstrating an initial operational capability within 270 days.
According to officials, the private sector’s response to the Genesis Mission has been “overwhelming.” Several corporations, including Nvidia, Dell, and AMD, have pledged to enhance AI-oriented computational resources at national laboratories.
In addressing concerns regarding increasing electricity demand from data centers, an official indicated that the heightened energy load would necessitate the development of new generation capacity, which would ultimately lead to lower per-unit electricity costs.
The official asserted that the overarching impact would be to “reduce electricity prices in the United States and bolster grid reliability.”
“Ultimately, the intersection of AI and hyperscaler development will serve as a mechanism for reducing electricity prices and augmenting grid reliability in the U.S.,” the official affirmed.
The order also calls for agencies to propose new scientific challenges and create a cohesive structure to coordinate research, data access, and collaborations spanning government, universities, and industry.
The National Science and Technology Council is designated to spearhead this initiative, bolstered by the support of federal data and AI councils.
Furthermore, the order establishes research fellowships at national laboratories and mandates the DOE to submit annual reports detailing platform performance, research progress, participation rates, and partnership outcomes.
“In this critical juncture, the challenges that lie ahead require a concerted national effort, analogous in urgency and ambition to the Manhattan Project, which played a pivotal role in our triumph during World War II and laid the groundwork for the Department of Energy and its national laboratories,” stated the executive order.
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